Purification and characterization of GP90, one of the envelope glycoproteins of respiratory syncytial virus.

نویسندگان

  • E E Walsh
  • J J Schlesinger
  • M W Brandriss
چکیده

The large glycoprotein, GP90, of respiratory syncytial virus (RSV) was purified by affinity chromatography using a monoclonal antibody. Hyperimmune rabbit antiserum directed specifically to the purified GP90 neutralized RSV to high titre but did not inhibit fusion of previously infected cells. 125I-labelled GP90 bound rapidly to HEp-2 cells in an unsaturable manner; binding was inhibited by the hyperimmune rabbit antiserum.

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عنوان ژورنال:
  • The Journal of general virology

دوره 65 ( Pt 4)  شماره 

صفحات  -

تاریخ انتشار 1984